Pollution Research - Effects of Air Pollution, Respiratory Illness, Industry

Pollution Research Today is a free monthly online journal that collates and summarizes the latest research about Pollution, including details on effects of air pollution, respiratory illness, industry.


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Outdoor Air Pollution: Particulate Matter Health Effects.

Chen TM, Gokhale J, Shofer S, Kuschner WG

From the Division of Pulmonary and Critical Care Medicine, Stanford University School of Medicine, Stanford, California (tmc, wgk); Alfred I. DuPont Hospital for Children and Jefferson Medical College of Thomas Jefferson University, Wilmington, Delaware (jg); the Division of Pulmonary, Allergy, and Critical Care Medicine, Duke University School of Medicine, Durham, North Carolina (ss); and the Pulmonary Section, US Department of Veterans Affairs Palo Alto Health Care System, Palo Alto, California (wgk).

Numerous investigations studying multiple populations across a variety of environmental settings have demonstrated a strong association between ambient air particulate matter and cardiopulmonary morbidity and mortality. In most studies, the effect size of ambient air particulate pollution on health outcomes is small. However, the exposed population worldwide is very large. Accordingly, particulate air pollution appears to be an important public health hazard that makes an important contribution to the total burden of disease and death in populations across the world. Much of the evidence linking ambient air particulates with adverse health effects is derived from population-based, observational research with potential unidentified confounding exposures, precluding definitive assessments about causation and providing limited mechanistic insights. A growing body of research suggests particulate-associated adverse health effects result from the induction of proinflammatory responses in the lower respiratory tract. Ambient air particulates may increase lung cancer risk.

Published 16 April 2007 in Am J Med Sci, 333(4): 235-243.
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